Cell-Mediated Immunity
Cell-mediated immunity is an integral part of our body’s immune system. This type of immunity is mediated by T-lymphocytes, also called T-cells. The functions of cell-mediated immunity are important and include defense against intracellular bacterial and viral infections. This is achieved by activating macrophages to destroy phagocytosed microbes via helper T-lymphocytes, or by directly killing infected cells via cytotoxic T-lymphocytes. Table of Contents Introduction to the Cell-Mediated Immunity The T-Cell Receptor Complex Helper T-Cell Subsets: Th0, Th1, and Th2 Cells Regulatory T-Cells, Cytotoxic T-Cells, Macrophages and Intraepithelial Lymphocytes Cytokines, Interferons, Interleukins and Colony Stimulating Factors Chemokines, Tumor Necrosis Factors and Transforming Growth Factors Therapeutic Blocking of Pathological Cytokines and Therapeutic Cytokines Review Questions References Introduction to the Cell-Mediated Immunity “Cell-Mediated Immunity”...